Product Name :
Mst3 Mouse Monoclonal Antibody [1G8]

Predicted band size :

Observed band size :

Synonyms:
epididymis secretory protein Li 95 antibody HEL-S-95 antibody Mammalian STE20 like protein kinase 3 antibody Mammalian STE20-like protein kinase 3 antibody Mammalian STE20-like protein kinase 3 C-terminal antibody Mammalian STE20-like protein kinase 3 N-terminal antibody Mammalian sterile 20-like 3 antibody MST-3 antibody MST3/C antibody MST3/N antibody 展开

Function :
Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily.Bis(pinacolato)diborane site The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38 MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an N-terminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK, JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily. Ksr-1 and Ksr-2 (also known as MST-2 and MST-1, respectively) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.

Antibody Type:
Mouse Monoclonal Antibody

Immunogen :
Amino acids 275-393 of MST-3 of human origin.

Species reactivity:
Human, Mouse, Rat

Verify application:
WB, IP, IF

Coupling :
unconjugated

Clone number:
1G8

RRID:

Form :
Liquid

Concentration :
2ug/ul

Storage instructions:
Store at +4℃

Storage buffer solution:
1.711017-85-5 uses 0 ml of PBS with

Subtype:
IgG1

Purification method :
Protein A affinity purified.PMID:33438187

ELTSA :

Molecular weight :
50/35 kDa

Positive control :
Hela, 293T, A-431.