Product Name :
NADPH oxidase 4 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Kidney oxidase 1 antibody Kidney oxidase-1 antibody Kidney superoxide producing NADPH oxidase antibody Kidney superoxide-producing NADPH oxidase antibody KOX 1 antibody KOX antibody Kox-1 antibody KOX1 antibody NADPH antibody NADPH oxidase 4 antibody 展开
Function :
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human Nox-4 81-180/578
Species reactivity:
Human, Mouse, Rat, Dog, Cow, Horse
Verify application:
WB, ELISA, IHC-P, FC, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1956318-42-5 supplier Avoid repeated freeze/thaw cycles.Fmoc-β-azido-Ala-OH Data Sheet The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33541802 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
64 KDa
Positive control :
EXpressed in brain, in all layers of the cerebellum, in pyramidal cells of the Ammon horn and in Purkinje cells (at protein level). Expressed in osteoclasts, leukocytes, kidney, liver and lung.